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Thursday, Nov 24, 2011 10:00 PM UTC2011-11-24T22:00:00Zl, M j, Y g:i A T

My life as a lab rat

I'm on the cutting edge of a promising new cancer treatment – if it doesn't kill me first

My life as a lab rat

 (Credit: iStockphoto/lculig)

The news couldn’t have been much worse. The timing couldn’t have been much better.

In August, one relatively healthy year after losing five centimeters of my scalp to malignant melanoma, my doctor told me there were some “troubling” new spots on my lungs – and that they were growing. A few weeks later, I awoke from the surgical biopsy, doped up and under an oxygen mask, and had my worst fears confirmed – the spots were malignant. Two weeks later, after I pointed out a peculiar bruise on my back during a routine follow-up, the diagnosis got even worse – that bruise was another malignant tumor.

In the space of days, I’d gone from someone whose friends had hastily branded a “survivor” to a woman with metastatic, Stage 4 cancer. But just as I was  blubbering through the news, my oncologist offered a life raft in a sea of panic. She explained that my immunologist, who’d recently led the clinical trials for Ipilimumab, the first new melanoma drug approved by the FDA in 30 years, was doing a new, Phase 1 clinical trial. It would combine Ipilimumab with another promising experimental drug, MDX-1106, and for a longer course of treatment. As an otherwise young, healthy person, I was a suitable candidate for the sole upcoming spot in the trial.

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Mary Elizabeth Williams

Mary Elizabeth Williams is a staff writer for Salon and the author of "Gimme Shelter: My Three Years Searching for the American Dream." Follow her on Twitter: @embeedubMore Mary Elizabeth Williams

Tuesday, Nov 1, 2011 12:00 AM UTC2011-11-01T00:00:00Zl, M j, Y g:i A T

Why bigger breasts eased my cancer recovery

After the mastectomy, I faced a dilemma: Should I reconstruct my body as it once was, or as I wish it had been?

“What size are you thinking?” the plastic surgeon asked.

I sat shirtless in the oversize, faux leather examining chair as he eyed the twin slits remaining on my chest four weeks after the mastectomy. I slipped a C-cup silicone breast prosthesis out of one side of the bra I’d worn into the office. “I used to be an A-cup. Can you match this?”

He palmed the three-dimensional, triangular blob and then pressed it against one of my incisions using the tips of his fingers to hold it in place. “I don’t see why not. You’re tall – you can carry any volume you want. Let’s go with a 350cc.”

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  More Wendy Colbert

Thursday, Oct 27, 2011 12:00 AM UTC2011-10-27T00:00:00Zl, M j, Y g:i A T

Why I made myself radioactive

The town of Basin, Mont., has been classified as a Superfund site, but, according to some, its pollution is a cure

radioactive mine
This article is excerpted from the Bellevue Literary Review's fall issue.

I get Geigered—to measure my personal level of radioactivity— before I enter the Merry Widow Health Mine. I register a measly, unradiating 0.1 millirads with barely a click from the Geiger counter. This is, or should be, normal. But I’m about to get dosed by radon gas, and the ‘before’ measurement is crucial to assessing the after-effects of one of the most intriguing and ironic features in the heart of mining country: health mines.

In the fall of 2008, I spent a lot of time in and around the tiny town of Basin, Montana. Basin, population 250, is a seemingly ruined, poverty-filled stretch along a frontage road threading off of Route 15 between Helena, the capital of the state, 40 miles to the north, and Butte, the famous mining town, 30 miles to the south. This is the middle to south-end of the Upper Clark Fork watershed. The Wild West. The heart of Montana mining territory in the late 1800s and early 1900s. Basin anchors an area littered with poisonous mine tailings, remnants of Superfund sites and cleanups, and all the gorgeous geology of an ancient, now post-ice age wilderness.

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  More Andrew C. Gottlieb

Tuesday, Oct 25, 2011 11:05 PM UTC2011-10-25T23:05:00Zl, M j, Y g:i A T

Panel: Boys should get HPV vaccine given to girls

Government advisors extend recommendation for vaccination against cancer-causing virus

HPV Vaccine Boys

A doctor holds the human papillomavirus vaccine Gardiasil in his hand at his Chicago office.  (Credit: AP/Charles Rex Arbogast)

ATLANTA (AP) — A vaccine against cervical cancer hasn’t been all that popular for girls. It may be even a harder sell for boys now that it’s been recommended for them too.

A government advisory panel on Tuesday decided that the vaccine should also be given to boys, in part to help prevent the cancer-causing virus through sex.

Public health officials have tried since 2006 to get parents to have their daughters vaccinated against the human papillomavirus, or HPV, which causes most of the cervical cancer in women.

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  More Mike Stobbe

Friday, Oct 21, 2011 6:50 PM UTC2011-10-21T18:50:00Zl, M j, Y g:i A T

Stop blaming Steve Jobs for his death

The Apple founder postponed treatment to explore alternative medicine. That doesn't mean his choices killed him

A woman holds an apple with a heart and the name of Steve Jobs written on it in front of a small memorial in his honour in San Francisco, California October 6, 2011.

A woman holds an apple in front of a small memorial to Steve Jobs in San Francisco, California October 6, 2011.  (Credit: Kimberly White / Reuters)

Hindsight is rarely 20/20. Instead, it has a terrible facility for illuminating all the mistakes made along the way, every wrong turn, each guess that should have gone seconded. It isn’t as kind with the well-played hands, and it almost never grants permission to say, Maybe that wasn’t so great, but it seemed the best choice at the time. Perhaps Steve Jobs would be alive today if he’d had surgery when his doctors first discovered a neuroendocrine tumor back in 2003, instead of spending nine months trying a battery of alternative treatments. Then again, maybe not.

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Mary Elizabeth Williams

Mary Elizabeth Williams is a staff writer for Salon and the author of "Gimme Shelter: My Three Years Searching for the American Dream." Follow her on Twitter: @embeedubMore Mary Elizabeth Williams

Monday, Oct 17, 2011 9:30 PM UTC2011-10-17T21:30:00Zl, M j, Y g:i A T

The death panels are already here

What happens when drug shortages spike? You hope to get lucky, like me

pill bottle2

 (Credit: aleksan via Shutterstock)

Bad news, right-wing nutjobs – it turns out that getting sick is not just a problem for those freeloading, uninsured socialist troublemakers. With drug shortages on the rise – and other countries tightening the reins on treatment coverage –  who lives and who doesn’t won’t be determined by politics but by the frightening economics of supply and demand.

A piece last month for the Wall Street Journal highlights the problem: Severe shortages of chemotherapy drugs, antibiotics and nutritional supplementation are leading to limited treatments and have caused “hundreds of clinical trials to be stopped.” Drug shortages have tripled in the last six years. And with a new high of 213 different drug shortages this year, patients with life-threatening conditions like high blood pressure, breast cancer, Kaposi’s sarcoma and leukemia have been affected.

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Mary Elizabeth Williams

Mary Elizabeth Williams is a staff writer for Salon and the author of "Gimme Shelter: My Three Years Searching for the American Dream." Follow her on Twitter: @embeedubMore Mary Elizabeth Williams

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