Republicans are hoping for a game changer with Wednesday's debate in Denver, but The Republican ticket can't even get Fox News on board with their vision for America.

Tonight, Ed (who is live from Denver tonight and tomorrow night!) welcomes Howard Fineman, NBC News Political Analyst and Editorial Director of the Huffington Post Media Group, for the latest from the Republican "rolling calamity."

Then, New Jersey Gov. Chris Christie predicts Mitt Romney will turn the presidential race "upside down" with his debate performance.  Susan Del Percio, Republican Strategist and MSNBC Contributor, and Chris Kofinis, Former Edwards Campaign Comm Director, will join Ed for a preview.

Its debate night (click here to watch them live until 8pET) in Massachusetts and Virginia and Democrats have Scott Brown and  Eric Cantor on the ropes.  

Felix Arroyo, Boston City Councilor At-Large will offer reaction and analysis on the Elizabeth Warren-Scott Brown debate and Wayne Powell will comment on his debate with House Majority Cantor.

And on the eve of early-voting in Ohio activists are sleeping overnight at the polling places. We'll go live to Cleveland where state Sen. Nina Turner (D-OH) is camping out.