GitHub2y
Protein-DNA binding affinity prediction
PDA-Pred predicts protein-DNA binding affinity using structure-based features and classes based on structure, function and percentage of binding site of protein. Generally, contact potenitals, ...
DNA origami suggests route to reusable, multifunctional biosensors
Using an approach called DNA origami, scientists have developed a technique that could lead to cheaper, reusable biomarker ...
DNA-binding C2H2 zinc finger proteins also regulate RNA processing, researchers discover
C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...
Frontiers2y
Hybrid_DBP: Prediction of DNA-binding proteins using hybrid features and convolutional neural networks
DNA-binding proteins (DBP) play an essential role in the genetics and evolution of organisms. A particular DNA sequence could provide underlying therapeutic benefits for hereditary diseases and ...
An ancient RNA-guided system could simplify delivery of gene editing therapies
A vast search of natural diversity has led scientists at MIT's McGovern Institute and the Broad Institute of MIT and Harvard ...
The Scientist4mon
DNA Polymerase Works in Short Bursts Rather than One Long Stretch
The team initially set out to study another replication machinery protein, single-stranded DNA-binding protein, and its interaction with DNA polymerase. However, they first needed to establish how the ...
A Protein Borrowed From Tardigrades Could Give Us Radiation Body Armor
The strangely adorable and resilient tardigrade, or water bear, just might hold the key to making cancer treatment a lot more ...
GitHub10mon
unccguolab/Prediction-of-DNA-and-RNA-binding-proteins
Non-NABP.fa: Fasta file of non-Nucleic acid-binding proteins. DSB.fa: Fasta file of double-stranded DNA binding proteins. SSB.fa: Fasta file of singel-stranded DNA binding proteins. RBP.fa: Fasta file ...
Single-molecule imaging reveals aberrant DNA-binding dynamics of cancer-linked chromatin remodelers
(a, b) Live-cell single-molecule imaging of the fully assembled SWI/SNF chromatin remodeler complex reveals distinct modes of ...
The Scientist4mon
A Novel Polymerase Reduces Stutter in Forensic DNA Analysis
“Our hypothesis is that strand slippage, or stutter, is caused by slippage of the DNA against the DNA polymerase that it's binding to, and that's performing the polymerization,” said David Mokry, a ...