A 4-year-old, 2.7 kg, neutered male lop-eared Himalayan rabbit presented to a veterinarian for lethargy, inappetence, and wet, stained fur and skin on the hind limbs and abdomen (Fig. 1).

For example, Himalayan rabbits carry the C gene, which is required for the development of pigments in the fur, skin, and eyes, and whose expression is regulated by temperature (Sturtevant ...