TANZANIA: SICKLE Cell Disease (SCD) remains a significant health burden, particularly in Africa where approximately 80 per ...

Results showed patients who underwent allogeneic HSCT while being treated with nonselective ... regeneration after chemotherapy or radiation therapy. However, nobody knew what the mechanism ...

Chimeric antigen receptor-T (CAR-T) cell therapy followed by allogeneic hematopoietic stem cell transplantation (allo-HSCT) leads to durable remissions and extended survival in patients with ...

Clin Lipidology. 2009;4(2):205-213. The conditioning or preparative program for HSCT typically involves a combination of irradiation and chemotherapy to completely destroy the host bone marrow (i ...

Calquence combination therapy showed improved progression-free survival in untreated mantle cell lymphoma patients ineligible for HSCT. Lumakras with Vectibix demonstrated superior progression-free ...

The next-generation sequencing (NGS)–based AlloHeme test accurately predicted relapse following allogeneic hematopoietic stem ...

Other companies looking at new ways to treat MPS I include Immusoft and Sigilon Therapeutics, which are developing cell-based therapies for the disease that could offer an alternative to HSCT that ...

The mucopolysaccharidosis market is witnessing a surge in innovation, driven by cutting-edge gene therapies, enzyme replacement treatments, and novel drug developments. The market is poised for ...

The trial (NCT04404283) included 230 patients with relapsed/refractory LBCL who were ineligible for auto-HSCT or CAR T-cell therapy. The patients were randomly assigned to receive brentuximab ...

Defibrotide prophylaxis after HSCT did not reduce sinusoidal obstructive syndrome incidence in high-risk pediatric patients, per retrospective study at 2025 Tandem Meeting.