Commercial SNP microarrays now provide comprehensive and affordable coverage of the human genome. However, some diseases have biologically relevant genomic regions that may require additional coverage ...

Microarrays are constructed from large pieces ... some marker chromosomes and aneuploidy. SNP arrays have the added advantage of the ability to identify polyploidy and long stretches of ...

The CalMaTe method calibrates preprocessed allele-specific copy number estimates (ASCNs) from DNA microarrays by controlling for single-nucleotide polymorphism-specific allelic crosstalk. The ...

Single nucleotide polymorphism (SNP) arrays are high-throughput DNA microarrays that originated from the early 2000s and are a powerful platform for simultaneously analyzing hundreds of thousands of ...

Microarray technology encompasses a few relatively well-established methods and numerous applications that are in various stages of development. Apart from their use as a tool for diagnostic ...

We show that we can easily and reliably detect unbalanced chromosomal aberrations of various sizes from as little as 250 ng of DNA on a single microarray ... were not detectable due to insufficient ...

What role do single nucleotide polymorphisms play in this? In terms of this study, a low F ST value for a SNP can be interpreted to mean that individuals from the subpopulation tend to share ...

The first use of SNP microarrays in a large autism study was by the Autism Genome Project, who used Affymetrix 10K SNP microarray data to perform high-resolution linkage analysis in over 1000 ...

Methods: Gravidas with positive NIPT results for RCAs who subsequently underwent amniocentesis for a single nucleotide polymorphism array (SNP array) were recruited. The degrees of concordance between ...

Methods CNV analysis was performed on 82 extensively phenotyped Canadian children with DCD, with or without co-occurring ADHD and/or reading disorder, and 2988 healthy European controls using ...