Harold Lecar

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{{Featured Author|[[User:Lecar|Harold Lecar ]]|
 
{{Featured Author|[[User:Lecar|Harold Lecar ]]|
 
[[Image:Harold-2.jpg|left|200px]]
 
[[Image:Harold-2.jpg|left|200px]]
<strong>Harold Lecar </strong> (b. in Brooklyn,USA, 18 Oct, 1935) was educated at Columbia University, where he received his PhD in
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<strong>Harold Lecar</strong> (b. in Brooklyn, USA, 18 Oct 1935) was educated at Columbia University, where he received his PhD in Physics in 1963 on the use of masers in microwave spectroscopy. From 1963 to 1985 he worked in the Biophysics Laboratory at the American National Institute of Neurological Disorders and Stroke (an NIH institute). Since 1985, he has been a Professor of Biophysics and Neurobiology at the University of California, Berkeley.
Physics in 1963 on the use of Masers in
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microwave spectroscopy. From 1963 to 1985, he worked in the
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Biophysics Laboratory, NINDS, NIH, where he was once Richard FitzHugh's
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only postdoc. Since 1985, he has been a Professor of Biophysics
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and Neurobiology at the University of California, Berkeley.
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In 1985, he received the Public Health Service Special Recognition  
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In 1985, Dr. Lecar received the American Public Health Service Special Recognition Award for “contributions to the understanding of the role of membrane ionic channels in producing electrical excitability and for pioneering work in advancing single-channel methods."
Award for “contributions to the understanding of the role of membrane ionic  
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channels in producing electrical excitability and for pioneering work in  
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advancing single-channel methods."
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Along with  Gerald Ehrenstein and Ralph Nossal, he observed the first single
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gated ion channels in a synthetic membrane and established the statistical picture of
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ion-channel gating.  With Ralph Nossal, he established the theory of how membrane
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noise produces action-potential threshold fluctuations. With Fred Sachs and
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Meyer Jackson, he initiated the patch-clamping of excitable cells grown in tissue
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culture which led to the study of numerous gated channels.  Cathy Morris and Dr. Lecar
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developed the reduced equations, which bear their name as a way to
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map the variety oscillatory behaviors seen in excitable cells.
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Along with Drs. Gerald Ehrenstein and Ralph Nossal, Dr. Lecar observed the first single gated ion channels in a synthetic membrane and established a statistical picture of ion-channel gating.  With Nossal, Lecar established the theory of how membrane noise produces action-potential threshold fluctuations. With Drs. Fred Sachs and Meyer Jackson, Dr. Lecar initiated the patch-clamping of excitable cells grown in tissue culture, which led to the study of numerous gated channels.  In the late 1970s, Drs. Catherine Morris and Lecar developed the now-termed [[Morris-Lecar_model]], a set of two-dimensional "reduced" excitation equations which describe a variety of oscillatory behaviors seen in excitable cells.
  
 
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Revision as of 18:42, 23 February 2008

Featured Author: Harold Lecar

Harold-2.jpg

Harold Lecar (b. in Brooklyn, USA, 18 Oct 1935) was educated at Columbia University, where he received his PhD in Physics in 1963 on the use of masers in microwave spectroscopy. From 1963 to 1985 he worked in the Biophysics Laboratory at the American National Institute of Neurological Disorders and Stroke (an NIH institute). Since 1985, he has been a Professor of Biophysics and Neurobiology at the University of California, Berkeley.

In 1985, Dr. Lecar received the American Public Health Service Special Recognition Award for “contributions to the understanding of the role of membrane ionic channels in producing electrical excitability and for pioneering work in advancing single-channel methods."

Along with Drs. Gerald Ehrenstein and Ralph Nossal, Dr. Lecar observed the first single gated ion channels in a synthetic membrane and established a statistical picture of ion-channel gating. With Nossal, Lecar established the theory of how membrane noise produces action-potential threshold fluctuations. With Drs. Fred Sachs and Meyer Jackson, Dr. Lecar initiated the patch-clamping of excitable cells grown in tissue culture, which led to the study of numerous gated channels. In the late 1970s, Drs. Catherine Morris and Lecar developed the now-termed Morris-Lecar_model, a set of two-dimensional "reduced" excitation equations which describe a variety of oscillatory behaviors seen in excitable cells.

Scholarpedia articles:

Morris-Lecar_model.


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