The Best Amazon Prime Comedy Series, Ranked

Bobby Bernstein
Updated February 28, 2025 53 items
Ranked By
736 votes
190 voters
Voting Rules
Vote up the best original comedies from Amazon. Originals and co-productions only.
Latest additions: Su Majestad, Clean Slate, The Sticky
Most divisive: Harlem
Over 100 Ranker voters have come together to rank this list of The Best Amazon Prime Comedy Series, Ranked

When it comes to streaming services, Amazon Prime has become a goldmine for comedy lovers, boasting an impressive lineup of original series that tickle the funny bone and engage audiences with their witty, inventive storytelling. Whether you're into sharp satire, charming dramedy, or offbeat humor, Prime has something to offer every comedy aficionado. If you're looking for some laughs with your Prime sub, we've curated a list of the best Amazon Prime comedy series – and we want you, the fans, to help us rank them. 

Our list includes some standout examples like Upload, where a digital afterlife becomes the backdrop for a hilarious exploration of life and love through the eyes of Robbie Amell’s recently deceased Nathan. Fleabag, starring Phoebe Waller-Bridge, offers biting humor and raw honesty as it chronicles the trials of a Londoner navigating grief and complicated relationships. Meanwhile, The Marvelous Mrs. Maisel dazzles with its vibrant portrayal of a 1950s housewife (played by Rachel Brosnahan) breaking into the male-dominated world of stand-up comedy.

With such a diverse selection of comedies, we’re curious to know which series tops your list. Find your favorite hilarious Prime series and submit your votes to influence the rankings.